Urinary Hydroxyproline as an Inflammation-Independent Biomarker of Inflammatory Bowel Disease

URN to cite this document:: urn:nbn:de:bvb:355-epub-585378
DOI to cite this document:: 10.5283/epub.58537

Huss, Muriel ; Elger, Tanja ; Loibl, Johanna ; Kandulski, Arne ; Binder, Benedicta ; Stoeckert, Petra ; Mester, Patricia ; Müller, Martina ; Buechler, Christa

; Tews, Hauke Christian

License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 26 Jun 2024 11:07

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Abstract

Predicting responses and monitoring the severity of inflammatory bowel disease (IBD) is challenging due to a lack of specific biomarkers. This study identifies urinary hydroxyproline, a marker of collagen turnover elevated in experimental colitis, as independent of conventional biomarkers like creatinine, glomerular filtration rate, C-reactive protein, and fecal calprotectin. Among 71 IBD ...