Distinct metabolomic and lipidomic profiles in serum samples of patients with primary sclerosing cholangitis

URN to cite this document:: urn:nbn:de:bvb:355-epub-585418
DOI to cite this document:: 10.5283/epub.58541

Fererberger, Tanja ; Buechler, Christa

; Kandulski, Arne ; Elger, Tanja ; Loibl, Johanna ; Schmid, Stephan

; Sommersberger, Stefanie ; Gunawan, Stefan ; Zundler, Sebastian ; Huss, Muriel ; Bettenworth, Dominik ; Kempa, Sally

; Weidlich, Simon ; Föh, Bandik ; Huang, Xinyu ; Grzegorzek, Marcin ; Derer-Petersen, Stefanie ; Günther, Ulrich L. ; Marquardt, Jens U. ; Kunst, Claudia ; Gülow, Karsten ; Müller, Martina ; Sina, Christian ; Schmelter, Franziska ; Tews, Hauke Christian

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Date of publication of this fulltext: 27 Jun 2024 11:45

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Abstract

Intoduction: Identification of specific metabolome and lipidome profile of patients with primary sclerosing cholangitis (PSC) is crucial for diagnosis, targeted personalized therapy, and more accurate risk stratification. Methods: Nuclear magnetic resonance (NMR) spectroscopy revealed an altered metabolome and lipidome of 33 patients with PSC [24 patients with inflammatory bowel disease ...