Retrospective analysis of the incidence and outcome of late acute and chronic graft-versus-host disease—an analysis from transplant centers across Europe

URN to cite this document:: urn:nbn:de:bvb:355-epub-586086
DOI to cite this document:: 10.5283/epub.58608

Langer, Ronja ; Lelas, Antonela ; Rittenschober, Michael ; Piekarska, Agnieszka ; Sadowska-Klasa, Alicja ; Sabol, Ivan

; Desnica, Lana ; Greinix, Hildegard ; Dickinson, Anne ; Inngjerdingen, Marit ; Lawitschka, Anita ; Vrhovac, Radovan ; Pulanic, Drazen ; Güneş, Sibel ; Klein, Stefan ; Moritz Middeke, Jan ; Grube, Matthias ; Edinger, Matthias ; Herr, Wolfgang ; Wolff, Daniel

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Date of publication of this fulltext: 04 Jul 2024 09:17

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Abstract

Introduction: Chronic graft-versus-host disease (cGvHD) is a serious late complication of allogeneic hematopoietic stem cell transplantation (allo-HSCT). Methods: This multicenter analysis determined the cumulative incidence (CI) of cGvHD and late acute GvHD (laGvHD) and its impact on transplantation-related mortality (TRM), relapse (R), and overall survival (OS) in 317 patients [296 adults, ...