Repetitive combined doses of bacteriophages and gentamicin protect against Staphylococcus aureus implant-related infections in Galleria mellonella

URN to cite this document:: urn:nbn:de:bvb:355-epub-588690
DOI to cite this document:: 10.5283/epub.58869

Mannala, Gopala Krishna

; Rupp, Markus

; Walter, Nike

; Youf, Raphaëlle

; Bärtl, Susanne ; Riool, Martijn

; Alt, Volker

License: Creative Commons Attribution Non-commercial No Derivatives 4.0
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Date of publication of this fulltext: 13 Aug 2024 09:11

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Abstract

Abstract Aims Bacteriophages infect, replicate inside bacteria, and are released from the host through lysis. Here, we evaluate the effects of repetitive doses of the Staphylococcus aureus phage 191219 and gentamicin against haematogenous and early-stage biofilm implant-related infections in Galleria mellonella. Methods For the haematogenous infection, G. mellonella larvae were implanted ...