Myristoylated PreS1-domain of the hepatitis B virus L-protein mediates specific binding to differentiated hepatocytes

URN to cite this document:: urn:nbn:de:bvb:355-epub-588973
DOI to cite this document:: 10.5283/epub.58897

Meier, Anja ; Mehrle, Stefan ; Weiss, Thomas S.

; Mier, Walter ; Urban, Stephan

License: Creative Commons Attribution 4.0
PDF - Published Version
(1MB)

Date of publication of this fulltext: 14 Aug 2024 14:12

Alternative links to fulltext:DOI DOI Publisher

Details

Preview

Export bibliographical data

Abstract

Abstract Chronic infection with the human hepatitis B virus (HBV) is a global health problem and a main cause of progressive liver diseases. HBV exhibits a narrow host range, replicating primarily in hepatocytes. Both host and hepatocyte specificity presumably involve specific receptor interactions on the target cell; however, direct evidence for this hypothesis is missing. Following the ...