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- URN to cite this document:
- urn:nbn:de:bvb:355-epub-589106
- DOI to cite this document:
- 10.5283/epub.58910
Abstract
Human hepatitis B virus (HBV) is characterized by a high species specificity and a distinct liver tropism. Within the liver, HBV replication occurs in differentiated and polarized hepatocytes. Accordingly, the in vitro HBV infection of primary human hepatocytes (PHHs) and the human hepatoma cell line, HepaRG, is restricted to differentiated, hepatocyte-like cells. Though preparations of PHH ...

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