Lipid Metabolism Disorders as Diagnostic Biosignatures in Sepsis

URN to cite this document:: urn:nbn:de:bvb:355-epub-591055
DOI to cite this document:: 10.5283/epub.59105

Birner, Charlotte ; Mester, Patricia ; Liebisch, Gerhard

; Höring, Marcus

; Schmid, Stephan

; Müller, Martina ; Pavel, Vlad

; Buechler, Christa

License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 05 Sep 2024 09:57

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Abstract

Critical illness causes disturbances in lipid metabolism. Here, we investigated the levels of apolipoprotein A-IV (apoA-IV), a regulator of triglyceride and cholesterol metabolism, in human sepsis. ApoA-IV (analyzed in 156 patients with systemic inflammatory response syndrome (SIRS)/sepsis) and cholesteryl ester (CE) (analyzed in 121 of these patients) were lower in patients compared to 43 ...