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'Living drugs' target CD70 in advanced renal tumors
Wagner, Kilian and Siska, Peter J.
(2024)
'Living drugs' target CD70 in advanced renal tumors.
Trends in Pharmacological Sciences 45 (9), pp. 757-759.
Date of publication of this fulltext: 12 Sep 2024 05:56
Article
DOI to cite this document: 10.5283/epub.59148
Abstract
Cellular therapies against solid tumors face three major barriers: low persistence, insufficient specificity, and high costs. In a recent study, Pal et al. tackle these challenges in kidney cancer by using novel, 'persistence-tuned' allogeneic chimeric antigen receptor (CAR) T cells directed against a stable antigen.
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| Item type | Article | ||||
| Journal or Publication Title | Trends in Pharmacological Sciences | ||||
| Publisher: | Elsevier - Cell Press | ||||
|---|---|---|---|---|---|
| Volume: | 45 | ||||
| Number of Issue or Book Chapter: | 9 | ||||
| Page Range: | pp. 757-759 | ||||
| Date | 29 July 2024 | ||||
| Institutions | Medicine > Lehrstuhl für Innere Medizin III (Hämatologie und Internistische Onkologie) | ||||
| Identification Number |
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| Keywords | CAR T cells, kidney cancer, renal cell carcinoma, allogeneic, CD70, VHL | ||||
| Dewey Decimal Classification | 600 Technology > 610 Medical sciences Medicine | ||||
| Status | Published | ||||
| Refereed | Yes, this version has been refereed | ||||
| Created at the University of Regensburg | Yes | ||||
| URN of the UB Regensburg | urn:nbn:de:bvb:355-epub-591482 | ||||
| Item ID | 59148 |
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