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'Living drugs' target CD70 in advanced renal tumors

URN to cite this document:
urn:nbn:de:bvb:355-epub-591482
DOI to cite this document:
10.5283/epub.59148
Wagner, Kilian ; Siska, Peter J.
Date of publication of this fulltext: 12 Sep 2024 05:56



Abstract

Cellular therapies against solid tumors face three major barriers: low persistence, insufficient specificity, and high costs. In a recent study, Pal et al. tackle these challenges in kidney cancer by using novel, 'persistence-tuned' allogeneic chimeric antigen receptor (CAR) T cells directed against a stable antigen.


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