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Wagner, Kilian ; Siska, Peter J.

'Living drugs' target CD70 in advanced renal tumors

Wagner, Kilian and Siska, Peter J. (2024) 'Living drugs' target CD70 in advanced renal tumors. Trends in Pharmacological Sciences 45 (9), pp. 757-759.

Date of publication of this fulltext: 12 Sep 2024 05:56
Article
DOI to cite this document: 10.5283/epub.59148


Abstract

Cellular therapies against solid tumors face three major barriers: low persistence, insufficient specificity, and high costs. In a recent study, Pal et al. tackle these challenges in kidney cancer by using novel, 'persistence-tuned' allogeneic chimeric antigen receptor (CAR) T cells directed against a stable antigen.



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Details

Item typeArticle
Journal or Publication TitleTrends in Pharmacological Sciences
Publisher:Elsevier - Cell Press
Volume:45
Number of Issue or Book Chapter:9
Page Range:pp. 757-759
Date29 July 2024
InstitutionsMedicine > Lehrstuhl für Innere Medizin III (Hämatologie und Internistische Onkologie)
Identification Number
ValueType
10.1016/j.tips.2024.07.002DOI
KeywordsCAR T cells, kidney cancer, renal cell carcinoma, allogeneic, CD70, VHL
Dewey Decimal Classification600 Technology > 610 Medical sciences Medicine
StatusPublished
RefereedYes, this version has been refereed
Created at the University of RegensburgYes
URN of the UB Regensburgurn:nbn:de:bvb:355-epub-591482
Item ID59148

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