Van der Waals (vdW) heterostructures consisting of bilayer graphene (BLG) encapsulated within monolayers of strong spin-orbit semiconductor WS or ferromagnetic semiconductor CrGeTe (CGT), are investigated. By performing realistic first-principles calculations we capture the essential BLG band structure features, including layer- and sublattice-resolved proximity spin-orbit or exchange couplings. For different relative twist angles (0 or 60) of the WS layers, and the magnetizations (parallel or antiparallel) of the CGT layers, with respect to BLG, the low energy bands are found and characterized by a series of fit parameters of model Hamiltonians. These effective models are then employed to investigate the tunability of the relevant energy dispersions by a gate field. For WS/BLG/WS encapsulation we find that twisting allows to turn off the spin splittings away from the points, due to opposite proximity-induced valley-Zeeman couplings in the two sheets of BLG. Close to the points the electron spins are polarized out of the plane. This polarization can be flipped by applying a gate field. As for magnetic CGT/BLG/CGT structures, we realize the recently proposed spin-valve effect, whereby a gap opens for antiparallel magnetizations of the CGT layers. Furthermore, we find that for the antiferromagnetic orientation the electron states away from have vanishingly weak proximity exchange, while the states close to remain spin polarized in the presence of an electric field. The induced magnetization can be flipped by changing the gate field. These findings should be useful for spin transport, spin filtering, and spin relaxation anisotropy studies of BLG-based vdW heterostructures.