Novel Electrospun Zwitterionic Nanofibers for Point‐Of‐Care Nucleic Acid Isolation Strategies Under Mild Conditions

URN to cite this document:: urn:nbn:de:bvb:355-epub-593317
DOI to cite this document:: 10.5283/epub.59331

Wieberneit, Alissa J.

; Wongkaew, Nongnoot

; Baeumner, Antje J.

License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 22 Oct 2024 06:36

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Abstract

Nucleic acid (NA) testing at the point-of-care requires efficient NA extraction followed by post-NA amplification to achieve necessary detection sensitivity. Nanofibers (NFs) are demonstrated to be an ideal solid surface in an NA extraction process but necessitate harsh conditions that interfere with the subsequent NA amplification process. It is demonstrated that novel, pH tunable, zwitterionic ...