Histologic Characterization of Tumor-Adjacent Mammary Adipose Tissue in Normal-Weight and Overweight/Obese Patients with Triple-Negative Breast Cancer

URN to cite this document:: urn:nbn:de:bvb:355-epub-595211
DOI to cite this document:: 10.5283/epub.59521

Wolf, Marietta ; Brochhausen, Christoph

; Ramakrishnan, Vignesh

; Iberl, Sabine ; Roth, Jonas ; Seitz, Stephan ; Burkhardt, Ralph

; Stadler, Sonja C.

License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 07 Nov 2024 13:25

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Abstract

Background: Obesity is a risk factor of several types of cancer, including breast cancer. In this study, we aimed to histologically characterize the adipose tissue of the tumor microenvironment (TME) of triple-negative breast cancer (TNBC) in overweight/obese versus normal-weight patients. Methods: TNBC tissue sections from normal-weight (BMI<25) and overweight/obese patients (BMI≥25) were ...