Effect of antibiotic drug use on outcome and therapy-related toxicity in patients with glioblastoma—A retrospective cohort study

URN to cite this document:: urn:nbn:de:bvb:355-epub-596585
DOI to cite this document:: 10.5283/epub.59658

Götz, Linda ; Ansafi, Tananeh ; Gerken, Michael ; Klinkhammer-Schalke, Monika ; Fischl, Anna ; Riemenschneider, Markus J.

; Proescholdt, Martin A.

; Bumes, Elisabeth

; Kölbl, Oliver ; Schmidt, Nils Ole

; Linker, Ralf A. ; Hau, Peter

; Haedenkamp, Tareq M.

License: Creative Commons Attribution 4.0
PDF - Published Version
(629kB)

Date of publication of this fulltext: 20 Nov 2024 14:20

Alternative links to fulltext:DOI Publisher

Details

Preview

Export bibliographical data

Abstract

Background. Glioblastoma (GB) is the most frequent malignant brain tumor and has a dismal prognosis. In other cancers, antibiotic use has been associated with severity of chemotherapy-induced toxicity and outcome. We investigated if these mechanisms are also involved in GB. Methods. We selected a cohort of 78 GB patients who received combined radiochemotherapy. We investigated if exposure to ...