Merging New and Old Concepts: Tandem Oxidative Radical‐Polar Crossover Ritter Amidation via Multicomponent Photo‐ and Electrochemical Processes

URN to cite this document:: urn:nbn:de:bvb:355-epub-597635
DOI to cite this document:: 10.5283/epub.59763

Lepori, Mattia

; Dey, Indrasish

; Pratley, Cassie

; Barham, Joshua P.

License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 11 Dec 2024 05:49

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Abstract

Nitrogen-containing drug molecules and pharmaceuticals are ubiquitous, rendering the construction of C−N bonds a crucial target in methodology development. The Ritter reaction is a well-established method for accessing C−N bonds by generating amide functionality through the reaction of carbocations and nitriles. Since its discovery back in 1948, the Ritter reaction has progressively advanced ...