Heussinger, Nicole ; Kontopantelis, Evangelos 
; Gburek‐Augustat, Janina ; Jenke, Andreas ; Vollrath, Gesa ; Korinthenberg, Rudolf ; Hofstetter, Peter ; Meyer, Sascha ; Brecht, Isabel ; Kornek, Barbara ; Herkenrath, Peter ; Schimmel, Mareike ; Wenner, Kirsten ; Häusler, Martin ; Lutz, Soeren ; Karenfort, Michael ; Blaschek, Astrid ; Smitka, Martin ; Karch, Stephanie ; Piepkorn, Martin ; Rostasy, Kevin ; Lücke, Thomas ; Weber, Peter ; Trollmann, Regina ; Klepper, Jörg ; Häussler, Martin ; Hofmann, Regina ; Weissert, Robert ; Merkenschlager, Andreas ; Buttmann, Mathias
; Gburek‐Augustat, Janina ; Jenke, Andreas ; Vollrath, Gesa ; Korinthenberg, Rudolf ; Hofstetter, Peter ; Meyer, Sascha ; Brecht, Isabel ; Kornek, Barbara ; Herkenrath, Peter ; Schimmel, Mareike ; Wenner, Kirsten ; Häusler, Martin ; Lutz, Soeren ; Karenfort, Michael ; Blaschek, Astrid ; Smitka, Martin ; Karch, Stephanie ; Piepkorn, Martin ; Rostasy, Kevin ; Lücke, Thomas ; Weber, Peter ; Trollmann, Regina ; Klepper, Jörg ; Häussler, Martin ; Hofmann, Regina ; Weissert, Robert ; Merkenschlager, Andreas ; Buttmann, Mathias 
Abstract
We retrospectively evaluated predictors of conversion to multiple sclerosis (MS) in 357 children with isolated optic neuritis (ON) as a first demyelinating event who had a median follow-up of 4.0 years. Multiple Cox proportional-hazards regressions revealed abnormal cranial magnet resonance imaging (cMRI; hazard ratio [HR]=5.94, 95% confidence interval [CI]=3.39-10.39, p<0.001), presence of ...
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