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Analysis of dopaminergic neuronal dysfunction in genetic and toxin‐induced models of Parkinson's disease in Drosophila

Navarro, Juan A. ; Heßner, Sabina ; Yenisetti, Sarat C. ; Bayersdorfer, Florian ; Zhang, Li ; Voigt, Aaron ; Schneuwly, Stephan ; Botella, Jose A.



Zusammenfassung

Drosophila melanogaster has contributed significantly to the understanding of disease mechanisms in Parkinson's disease (PD) as it is one of the very few PD model organisms that allow the study of age-dependent behavioral defects, physiology and histology, and genetic interactions among different PD-related genes. However, there have been contradictory results from a number of recent reports ...

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