| Item type: | Article | ||||
|---|---|---|---|---|---|
| Journal or Publication Title: | International Ophthalmology | ||||
| Publisher: | SPRINGER | ||||
| Place of Publication: | DORDRECHT | ||||
| Volume: | 34 | ||||
| Number of Issue or Book Chapter: | 4 | ||||
| Page Range: | pp. 773-779 | ||||
| Date: | 2014 | ||||
| Institutions: | Medicine > Lehrstuhl für Augenheilkunde Medicine > Zentren des Universitätsklinikums Regensburg > Zentrum für Klinische Studien | ||||
| Identification Number: |
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| Keywords: | ASSOCIATIONS; | ||||
| Dewey Decimal Classification: | 600 Technology > 610 Medical sciences Medicine | ||||
| Status: | Published | ||||
| Refereed: | Yes, this version has been refereed | ||||
| Created at the University of Regensburg: | Yes | ||||
| Item ID: | 61314 |
Web of ScienceAbstract
We assessed the value of preoperative optical coherence tomography (OCT) for predicting the visual outcome for patients undergoing macular surgery for epiretinal membranes (ERMs). In a retrospective trial, we analyzed themedical charts of patients who had received surgery for ERMs between January and August 2011. The best-corrected pre-and postoperative logMAR visual acuitywas assessed. We ...
Abstract
We assessed the value of preoperative optical coherence tomography (OCT) for predicting the visual outcome for patients undergoing macular surgery for epiretinal membranes (ERMs). In a retrospective trial, we analyzed themedical charts of patients who had received surgery for ERMs between January and August 2011. The best-corrected pre-and postoperative logMAR visual acuitywas assessed. We pre-and postoperatively measured the central foveal thickness with high-resolution spectral-domainOCT and analyzed the structure of the outer retinal layers (retinal pigment epithelium, photoreceptors, and external limiting membrane) before and after surgery. The study included 49 patients (23 male, 27 female) with an average age of 69 years (SD 6.7) who had received macular surgery during the above-mentioned period. For phakic eyes (n = 34), treatment had also included phacoemulsification and intraocular lens implantation. Postoperative follow-up examinations and OCT controls had been conducted after an average of 9 weeks (SD5). The mean improvement in visual acuity was 2.4 lines (SD 2.3; p < 0.001). For patients with phakic eyes, the combination of vitrectomy and cataract surgery resulted in a slightly better, but insignificant increase in visual acuity than for patients with primary pseudophakia (Delta = 0.05, p = 0.46). On average, central foveal thickness regressed by 94 mu m (SD 129 mu m). Linear regression showed a significant linear relationship between the reduction of central foveal thickness and improvement of visual acuity (R-2 = 0.16, B = 0.71, p = 0.004). A decrease in foveal thickness by 100 lm resulted in an increase in visual acuity by 0.71 lines. Visual improvement did not significantly differ between the group of patients with intact outer retinal layers before surgery and the group of patientswith preoperative defects of the retina (p = 0.085). We found a significant linear relationship between the reduction of central foveal thickness and improvement of visual acuity for patients undergoing surgery for ERM. However, the preoperative OCT status (intact vs. broken) of the outer retinal layers did not correlate with the change in visual acuity.
Metadata last modified: 19 Dec 2024 08:08
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