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Prophylaxis and treatment of GVHD: EBMT–ELN working group recommendations for a standardized practice

Ruutu, T ; Gratwohl, A ; de Witte, T ; Afanasyev, B ; Apperley, J ; Bacigalupo, A ; Dazzi, F ; Dreger, P ; Duarte, R ; Finke, J ; Garderet, L ; Greinix, H ; Holler, E ; Kröger, N ; Lawitschka, A ; Mohty, M ; Nagler, A ; Passweg, J ; Ringdén, O ; Socié, G ; Sierra, J ; Sureda, A ; Wiktor-Jedrzejczak, W ; Madrigal, A ; Niederwieser, D



Abstract

GVHD remains the major impediment to broader application of allogeneic haematopoietic SCT. It can be prevented completely, but at the expense of other complications, rejection, relapse or delayed immune reconstitution. No optimal prevention or treatment method has been defined. This is reflected by enormous heterogeneity in approaches in Europe. Retrospective comparisons between different ...

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