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Synthesis of an Amino Acid with Protected Cyclen Side Chain Functionality

Miltschitzky, S. and König, B. (2004) Synthesis of an Amino Acid with Protected Cyclen Side Chain Functionality. Syn. Commun. 34, 2077 – 2084.

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Starting from glutamic acid an artificial amino acid with 1,4,7,10-tetraazacyclododecane (cyclen) side chain functionality is prepared. The orthogonal protected building block allows the facile introduction of a metal ion binding site into peptide structures.

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Item type:Article
Institutions:Chemistry and Pharmacy > Institut für Organische Chemie > Lehrstuhl Prof. Dr. Burkhard König
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Keywords:1,4,7,10-Tetraazacyclododecane; Molecular recognition; Peptide synthesis; Transition metal binding
Dewey Decimal Classification:500 Science > 540 Chemistry & allied sciences
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:6238
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