Abstract
Purpose: The authors present a stochastic framework for radiotherapy patient positioning directly utilizing radiographic projections. This framework is developed to be robust against anatomical non-rigid deformations and to cope with challenging imaging scenarios, involving only a few cone beam CT projections from short arcs. Methods: Specifically, a Bayesian estimator (BE) is explicitly derived ...
Abstract
Purpose: The authors present a stochastic framework for radiotherapy patient positioning directly utilizing radiographic projections. This framework is developed to be robust against anatomical non-rigid deformations and to cope with challenging imaging scenarios, involving only a few cone beam CT projections from short arcs. Methods: Specifically, a Bayesian estimator (BE) is explicitly derived for the given scanning geometry. This estimator is compared to reference methods such as chamfer matching (CM) and the minimization of the median absolute error adapted as tools of robust image processing and statistics. In order to show the performance of the stochastic short-arc patient positioning method, a CIRS IMRT thorax phantom study is presented with movable markers and the utilization of an Elekta Synergy (R) XVI system. Furthermore, a clinical prostate CBCT scan of a Varian (R) On-Board Imager (R) system is utilized to investigate the robustness of the method for large variations of image quality (anterior-posterior vs lateral views). Results: The results show that the BE shifts reduce the initial setup error of up to 3 cm down to 3 mm at maximum for an imaging arc as short as 10 degrees while CM achieves residual errors of 7 mm at maximum only for arcs longer than 40 degrees. Furthermore, the BE can compensate robustly for low image qualities using several low quality projections simultaneously. Conclusions: In conclusion, an estimation method for marker-based patient positioning for short imaging arcs is presented and shown to be robust and accurate for deformable anatomies. (C) 2012 American Association of Physicists in Medicine. [http://dx.doi.org/10.1118/1.4764483]
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