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Structural basis of highly conserved ribosome recycling in eukaryotes and archaea

Becker, Thomas ; Franckenberg, Sibylle ; Wickles, Stephan ; Shoemaker, Christopher J. ; Anger, Andreas M. ; Armache, Jean-Paul ; Sieber, Heidemarie ; Ungewickell, Charlotte ; Berninghausen, Otto ; Daberkow, Ingo ; Karcher, Annette ; Thomm, Michael ; Hopfner, Karl-Peter ; Green, Rachel ; Beckmann, Roland



Abstract

Ribosome-driven protein biosynthesis is comprised of four phases: initiation, elongation, termination and recycling. In bacteria, ribosome recycling requires ribosome recycling factor and elongation factor G, and several structures of bacterial recycling complexes have been determined. In the eukaryotic and archaeal kingdoms, however, recycling involves the ABC-type ATPase ABCE1 and little is ...

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