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Differential Gene Regulation under Altered Gravity Conditions in Follicular Thyroid Cancer Cells: Relationship between the Extracellular Matrix and the Cytoskeleton

Ulbrich, Claudia ; Pietsch, Jessica ; Grosse, Jirka ; Wehland, Markus ; Schulz, Herbert ; Saar, Katrin ; Hübner, Norbert ; Hauslage, Jens ; Hemmersbach, Ruth ; Braun, Markus ; van Loon, Jack ; Vagt, Nicole ; Egli, Marcel ; Richter, Peter ; Einspanier, Ralf ; Sharbati, Soroush ; Baltz, Theo ; Infanger, Manfred ; Ma, Xiao ; Grimm, Daniela



Abstract

Extracellular matrix proteins, adhesion molecules, and cytoskeletal proteins form a dynamic network interacting with signalling molecules as an adaptive response to altered gravity. An important issue is the exact differentiation between real microgravity responses of the cells or cellular reactions to hypergravity and/or vibrations. To determine the effects of real microgravity on human cells, ...

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