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Dopamine-dependent neurodegeneration in Drosophila models of familial and sporadic Parkinson's disease

Bayersdorfer, Florian ; Voigt, Aaron ; Schneuwly, Stephan ; Botella, José A.



Zusammenfassung

Parkinson's disease has been found to be caused by both, genetic and environmental factors. Despite the diversity of causes involved, a convergent pathogenic mechanism might underlie the special vulnerability of dopaminergic neurons in different forms of Parkinsonism. In recent years, a number of reports have proposed dopamine as a common player responsible in the loss of dopaminergic neurons ...

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