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Alternative mechanisms for tiotropium

Bateman, E.D. ; Rennard, S. ; Barnes, P.J. ; Dicpinigaitis, P.V. ; Gosens, R. ; Gross, N.J. ; Nadel, J.A. ; Pfeifer, M. ; Racké, K. ; Rabe, K.F. ; Rubin, B.K. ; Welte, T. ; Wessler, I.



Zusammenfassung

Tiotropium is commonly used in the treatment of chronic obstructive pulmonary disease. Although largely considered to be a long-acting bronchodilator, its demonstrated efficacy in reducing the frequency of exacerbations and preliminary evidence from early studies indicating that it might slow the rate of decline in lung function suggested mechanisms of action in addition to simple ...

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