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Myocilin promotes substrate adhesion, spreading and formation of focal contacts in podocytes and mesangial cells

Goldwich, Andreas ; Scholz, Michael ; Tamm, Ernst R.



Zusammenfassung

Myocilin, a secreted glycoprotein of the olfactomedin family, is constitutively expressed in podocytes of the rat kidney and induced in mesangial cells during mesangioproliferative glomerulonephritis. As myocilin has been found to be associated with fibrillar components of the extracellular matrix, and adhesive properties have been shown for other members of the olfactomedin family, we ...

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