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Targeting Heat Shock Protein 90 in Pancreatic Cancer Impairs Insulin-like Growth Factor-I Receptor Signaling, Disrupts an Interleukin-6/Signal-Transducer and Activator of Transcription 3/Hypoxia-Inducible Factor-1α Autocrine Loop, and Reduces Orthotopic Tumor Growth
Lang, Sven A., Moser, Christian, Gaumann, Andreas, Klein, Dagmar, Glockzin, Gabriel, Popp, Felix C., Dahlke, Marc H., Piso, Pompiliu, Schlitt, Hans J., Geissler, Edward K. and Stoeltzing, Oliver (2007) Targeting Heat Shock Protein 90 in Pancreatic Cancer Impairs Insulin-like Growth Factor-I Receptor Signaling, Disrupts an Interleukin-6/Signal-Transducer and Activator of Transcription 3/Hypoxia-Inducible Factor-1α Autocrine Loop, and Reduces Orthotopic Tumor Growth. Clinical Cancer Research 13 (21), pp. 6459-6468.Date of publication of this fulltext: 19 Dec 2024 13:37
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| Item type | Article | ||||
| Journal or Publication Title | Clinical Cancer Research | ||||
| Publisher: | AMER ASSOC CANCER RESEARCH | ||||
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| Place of Publication: | PHILADELPHIA | ||||
| Volume: | 13 | ||||
| Number of Issue or Book Chapter: | 21 | ||||
| Page Range: | pp. 6459-6468 | ||||
| Date | 2007 | ||||
| Institutions | Medicine > Lehrstuhl für Chirurgie Medicine > Lehrstuhl für Pathologie | ||||
| Identification Number |
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| Keywords | HYPOXIA-INDUCIBLE FACTOR-1-ALPHA; HSP90 INHIBITOR 17-ALLYLAMINO-17-DEMETHOXYGELDANAMYCIN; GASTRIC-CANCER; CELL-LINE; PROMOTER ACTIVITY; CARCINOMA CELLS; COLON-CANCER; NUDE-MICE; EXPRESSION; ANGIOGENESIS; | ||||
| Dewey Decimal Classification | 600 Technology > 610 Medical sciences Medicine | ||||
| Status | Published | ||||
| Refereed | Yes, this version has been refereed | ||||
| Created at the University of Regensburg | Yes | ||||
| Item ID | 68729 |
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