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Neuroendocrine–immune interactions in synovitis

Cutolo, Maurizio ; Straub, Rainer H ; Bijlsma, Johannes WJ



Zusammenfassung

Synovial tissue lines the noncartilaginous surfaces of synovial joints and supplies these avascular structures with nutrients. In diseases such as rheumatoid arthritis, inflammation of the synovial tissue - synovitis induces diffuse damage to the joints. The presence of functional receptors for glucocorticoids, androgens and estrogens in synoviocytes might link inflammation and the endocrine ...

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