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-Endorphin, Met-enkephalin and corresponding opioid receptors within synovium of patients with joint trauma, osteoarthritis and rheumatoid arthritis

Mousa, S. A ; Straub, R. H ; Schafer, M. ; Stein, C.



Zusammenfassung

Objective: Intra- articularly applied opioid agonists or antagonists modulate pain after knee surgery and in chronic arthritis. Therefore, the expression of b- endorphin ( END), Met- enkephalin ( ENK), and mu and delta opioid receptors ( ORs) within synovium of patients with joint trauma ( JT), osteoarthritis ( OA) and rheumatoid arthritis ( RA) were examined. Methods: Synovial samples were ...

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