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In vivo treatment with the herbal phenylethanoid acteoside ameliorates intestinal inflammation in dextran sulphate sodium-induced colitis

Hausmann, M ; Obermeier, F ; Paper, D H ; Balan, K ; Dunger, N ; Menzel, K ; Falk, W ; Schoelmerich, J ; Herfarth, H ; Rogler, G



Zusammenfassung

Recently we demonstrated that in inflammatory bowel disease (IBD) macrophage-oxidative burst activity is increased and NADPH oxidase mRNA is induced. The herbal phenylethanoid acteoside isolated from Plantago lanceolata L. was shown to exhibit anti-oxidative potential. Using the dextran sulphate sodium (DSS)-induced colitis model, in this study we have assessed whether systemic application of ...

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