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Prevalence of familial pancreatic cancer in Germany

Bartsch, Detlef K. ; Kress, Ralf ; Sina‐Frey, Mercedes ; Grützmann, Robert ; Gerdes, Berthold ; Pilarsky, Christian ; Heise, Joachim W. ; Schulte, Klaus‐Martin ; Colombo‐Benkmann, Mario ; Schleicher, Cristina ; Witzigmann, Helmut ; Pridöhl, Olaf ; Ghadimi, Michael B. ; Horstmann, Olaf ; von Bernstorff, Wolfgang ; Jochimsen, Lisa ; Schmidt, Jan ; Eisold, Sven ; Estévéz‐Schwarz, Lope ; Hahn, Stephan A. ; Schulmann, Karsten ; Böck, Wolfgang ; Gress, Thomas M. ; Zügel, Nikolaus ; Breitschaft, Karl ; Prenzel, Klaus ; Messmann, Helmut ; Endlicher, Esther ; Schneider, Margarete ; Ziegler, Andreas ; Schmiegel, Wolff ; Schäfer, Helmut ; Rothmund, Matthias ; Rieder, Harald



Abstract

Based on several case-control studies, it has been estimated that familial aggregation and genetic susceptibility play a role in up to 10% of patients with pancreatic cancer, although conclusive epidemiologic data are still lacking. Therefore, we evaluated the prevalence of familial pancreatic cancer and differences to its sporadic form in a. prospective multicenter trial. A total of 479 ...

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