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High Efficacy of Clonal Growth and Expansion of Adult Neural Stem Cells

Wachs, Frank-Peter ; Couillard-Despres, Sebastien ; Engelhardt, Maren ; Wilhelm, Daniel ; Ploetz, Sonja ; Vroemen, Maurice ; Kaesbauer, Johanna ; Uyanik, Goekhan ; Klucken, Jochen ; Karl, Claudia ; Tebbing, Johanna ; Svendsen, Clive ; Weidner, Norbert ; Kuhn, Hans-Georg ; Winkler, Juergen ; Aigner, Ludwig



Abstract

Neural stem cells (NSCs) from the adult central nervous system are currently being investigated for their potential use in autologous cell replacement strategies. High expansion rates of NSCs in culture are crucial for the generation of a sufficient amount of cells needed for transplantation. Here, we describe efficient growth of adult NSCs in Neurobasal medium containing B27 supplement under ...

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