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Die Rheumatoide Arthritis: Neuentwicklungen in der Pathogenese unter besonderer Berücksichtigung der synovialen Fibroblasten

Seemayer, C. A. ; Distler, O. ; Kuchen, S. ; Müller-Ladner, U. ; Michel, B. A. ; Neidhart, M. ; Gay, R. E. ; Gay, S.



Zusammenfassung

Rheumatoid arthritis (RA) is a chronic inflammatory disease, which is mainly characterized by synovial hyperplasia, pathological immune phenomena and progressive destruction of the affected joints. Various cell types are involved in the pathogenesis of RA including T cells, antigen presenting cells, and endothelial cells. Recent experimental evidence suggests that the CD40/CD154 system might play ...

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