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Release of prostaglandin E2, IL‐6 and IL‐8 from human oral epithelial culturemodels after exposure to compounds of dental materials

Schmalz, Gottfried ; Schweikl, Helmut ; Hiller, Karl‐Anton



Abstract

A three-dimensional human tissue model based on TR146 cells isolated from a squamous cell carcinoma of the buccal mucosa was used to test for the release of the proinflammatory molecules prostaglandin E-2 (PGE(2)), interleukin 6 (IL-6), and interleukin 8 (IL-8) after exposure to nickel chloride (NiCl2), cobalt chloride (CoCl2), palladium chloride (PdCl2), and triethylene glycol dimethacrylate ...

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