Meglumine-enhanced water solubility and stability of quercetin at moderate pH via liposome encapsulation

URN to cite this document:: urn:nbn:de:bvb:355-epub-746286
DOI to cite this document:: 10.5283/epub.74628

Holzhausen, Ferdinand ; Fusina, Adrien ; Loessl, Michael

; Touraud, Didier ; Baeumner, Antje J.

; Nardello-Rataj, Véronique ; Kunz, Werner

License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 14 Jan 2025 12:04

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Abstract

In the present work, the flavonoid quercetin was encapsulated into liposomes from an aqueous solution using meglumine as solubility enhancer and stabilizer for quercetin. This study was a proof of principle to demonstrate the feasibility of the pH-driven (or pH jump) method even with very oxidation-sensitive polyphenols. We thus investigated meglumine addition together with the standard thin-film ...