Dickkopf 3 as a New Monitoring Tool for Kidney Function After Living Kidney Donation

URN to cite this document:: urn:nbn:de:bvb:355-epub-746292
DOI to cite this document:: 10.5283/epub.74629

Schuster, Antonia Margarete

; Steines, Louisa ; Banas, Bernhard

; Bergler, Tobias

License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 13 Jan 2025 09:15

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Abstract

Background: Even today, a non-invasive biomarker to identify donors with enhanced risk for renal impairment is missing. Dickkopf 3 (DKK3) can cause tubulointerstitial fibrosis and is associated with rapid eGFR loss. The aim of our work was to analyze whether DKK3 can be used as a non-invasive alert marker for an increased risk of loss of kidney function in living kidney donors (LKDs). Methods: ...