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Holzapfel, Dominik Emanuel ; Kappenschneider, Tobias ; Schuster, Marie Farina ; Pagano, Stefano ; Azar, Fady ; Holzapfel, Sabrina ; Meyer, Matthias

Influence of parkinson’s disease on complications and revisions in total hip and knee arthroplasty: insights from a matched pair analysis

Holzapfel, Dominik Emanuel , Kappenschneider, Tobias, Schuster, Marie Farina, Pagano, Stefano, Azar, Fady, Holzapfel, Sabrina und Meyer, Matthias (2025) Influence of parkinson’s disease on complications and revisions in total hip and knee arthroplasty: insights from a matched pair analysis. International Orthopaedics.

Veröffentlichungsdatum dieses Volltextes: 30 Jan 2025 06:55
Artikel
DOI zum Zitieren dieses Dokuments: 10.5283/epub.74764


Zusammenfassung

Purpose The outcome of elective total joint arthroplasty (TJA) in patients with Parkinson’s disease (PD) is controversial due to the concomitant risk profile. This study investigated postoperative complications and revision rates following total hip (THA) and knee arthroplasty (TKA) in patients with PD. Methods Ninety-six patients with PD undergoing THA or TKA were matched 1:1 with non-PD ...

Purpose
The outcome of elective total joint arthroplasty (TJA) in patients with Parkinson’s disease (PD) is controversial due to the concomitant risk profile. This study investigated postoperative complications and revision rates following total hip (THA) and knee arthroplasty (TKA) in patients with PD.
Methods
Ninety-six patients with PD undergoing THA or TKA were matched 1:1 with non-PD patients using propensity score matching for age, sex and comorbidity (Charlson Comorbidity index, CCI). Rates of revisions, medical and surgical complications were compared. Univariate and multivariate regression analyses were calculated.
Results
PD patients exhibited higher rates of revision-surgeries within 90 days (13.5% vs. 5.2%; p = 0.048), medical complications (68.8% vs. 43.8%; p < 0.001) and surgical complications (40.6% vs. 21.9%; p = 0.005). Multivariate regression analysis confirmed PD as a significant risk factor for complications and long-term revision-surgeries.
Conclusion
PD increases the risk of adverse outcomes following THA and TKA. Improvements in pre-operative planning and post-operative care are critical to the improvement of outcomes in this vulnerable population.



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Details

DokumentenartArtikel
Titel eines Journals oder einer ZeitschriftInternational Orthopaedics
Verlag:Springer
Datum24 Januar 2025
InstitutionenMedizin > Lehrstuhl für Kinder- und Jugendmedizin
Medizin > Lehrstuhl für Orthopädie
Identifikationsnummer
WertTyp
10.1007/s00264-024-06398-9DOI
Stichwörter / KeywordsParkinson’s disease · TJA · TKA · THA · Postoperative complications · Revision surgery
Dewey-Dezimal-Klassifikation600 Technik, Medizin, angewandte Wissenschaften > 610 Medizin
StatusVeröffentlicht
BegutachtetJa, diese Version wurde begutachtet
An der Universität Regensburg entstandenZum Teil
URN der UB Regensburgurn:nbn:de:bvb:355-epub-747641
Dokumenten-ID74764

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