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Influence of parkinson’s disease on complications and revisions in total hip and knee arthroplasty: insights from a matched pair analysis
Holzapfel, Dominik Emanuel
, Kappenschneider, Tobias, Schuster, Marie Farina, Pagano, Stefano, Azar, Fady, Holzapfel, Sabrina and Meyer, Matthias
(2025)
Influence of parkinson’s disease on complications and revisions in total hip and knee arthroplasty: insights from a matched pair analysis.
International Orthopaedics.
Date of publication of this fulltext: 30 Jan 2025 06:55
Article
DOI to cite this document: 10.5283/epub.74764
Abstract
Purpose The outcome of elective total joint arthroplasty (TJA) in patients with Parkinson’s disease (PD) is controversial due to the concomitant risk profile. This study investigated postoperative complications and revision rates following total hip (THA) and knee arthroplasty (TKA) in patients with PD. Methods Ninety-six patients with PD undergoing THA or TKA were matched 1:1 with non-PD ...
Purpose
The outcome of elective total joint arthroplasty (TJA) in patients with Parkinson’s disease (PD) is controversial due to the concomitant risk profile. This study investigated postoperative complications and revision rates following total hip (THA) and knee arthroplasty (TKA) in patients with PD.
Methods
Ninety-six patients with PD undergoing THA or TKA were matched 1:1 with non-PD patients using propensity score matching for age, sex and comorbidity (Charlson Comorbidity index, CCI). Rates of revisions, medical and surgical complications were compared. Univariate and multivariate regression analyses were calculated.
Results
PD patients exhibited higher rates of revision-surgeries within 90 days (13.5% vs. 5.2%; p = 0.048), medical complications (68.8% vs. 43.8%; p < 0.001) and surgical complications (40.6% vs. 21.9%; p = 0.005). Multivariate regression analysis confirmed PD as a significant risk factor for complications and long-term revision-surgeries.
Conclusion
PD increases the risk of adverse outcomes following THA and TKA. Improvements in pre-operative planning and post-operative care are critical to the improvement of outcomes in this vulnerable population.
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Details
| Item type | Article | ||||
| Journal or Publication Title | International Orthopaedics | ||||
| Publisher: | Springer | ||||
|---|---|---|---|---|---|
| Open Access Type: | DEAL (Springer) | ||||
| Date | 24 January 2025 | ||||
| Institutions | Medicine > Lehrstuhl für Kinder- und Jugendmedizin Medicine > Lehrstuhl für Orthopädie | ||||
| Identification Number |
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| Keywords | Parkinson’s disease · TJA · TKA · THA · Postoperative complications · Revision surgery | ||||
| Dewey Decimal Classification | 600 Technology > 610 Medical sciences Medicine | ||||
| Status | Published | ||||
| Refereed | Yes, this version has been refereed | ||||
| Created at the University of Regensburg | Partially | ||||
| URN of the UB Regensburg | urn:nbn:de:bvb:355-epub-747641 | ||||
| Item ID | 74764 |
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