Long-term Elevation of Complement Factors in Cerebrospinal Fluid of Patients With Borna Disease Virus 1 Encephalitis

URN to cite this document:: urn:nbn:de:bvb:355-epub-747910
DOI to cite this document:: 10.5283/epub.74791

Bauswein, Markus

; Zoubaa, Saida ; Toelge, Martina ; Eidenschink, Lisa ; Riemenschneider, Markus J.

; Neumann, Bernhard

; Lee, De-Hyung ; Eid, Ehab ; Tappe, Dennis ; Niller, Hans Helmut ; Gessner, André

; Schmidt, Barbara

; Bülow, Sigrid

; Angstwurm, Klemens

License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 28 Jan 2025 16:32

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Abstract

Background Borna disease virus 1 (BoDV-1) causes rare but severe zoonotic infections in humans, presenting as encephalitis. The case-fatality risk is very high and no effective countermeasures have been established so far. An immunopathology is presumed, while data on immune responses in humans are limited. Evidence of a role of the complement system in various neurological disorders and in ...