We compute all helicity amplitudes for the scattering of five partons in two-loop QCD in all the relevant flavor configurations, retaining all contributing color structures. We employ tensor projection to obtain helicity amplitudes in the ’t Hooft-Veltman scheme starting from a set of primitive amplitudes. Our analytic results are expressed in terms of massless pentagon functions, and are easy to evaluate numerically. These amplitudes provide important input to investigations of soft-collinear factorization and to studies of the high-energy limit.