Visible-Light Photoredox Catalytic Direct N-(Het)Arylation of Lactams

URN to cite this document:: urn:nbn:de:bvb:355-epub-750309
DOI to cite this document:: 10.5283/epub.75030

Boselli, Monica Fiorenza

; Ghosh, Indrajit

; Intini, Niccolò

; Fattalini, Marco

; Puglisi, Alessandra

; König, Burkhard

; Benaglia, Maurizio

License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 18 Feb 2025 11:34

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Abstract

Lactam rings are essential structural motifs in organic chemistry, widely present in natural products and clinically important drugs, such as antibiotics and antiepileptics. Existing methods for synthesizing N-functionalized lactams often require harsh conditions, toxic reagents, or complex catalytic systems. Here, we report a mild and efficient photochemical approach for generating N-centered ...