| Veröffentlichte Version Download ( PDF | 710kB) | Lizenz: Creative Commons Namensnennung 4.0 International |
Right Ventricular Systolic Dysfunction Predicts Recovery of Left Ventricular Systolic Function and Reduced Quality of Life in Patients With Arrhythmia‐Induced Cardiomyopathy
Körtl, Thomas, Mühleck, Franziska, Baum, Paul, Resch, Markus, Meindl, Christine
, Üçer, Ekrem, Maier, Lars S.
, Wachter, Rolf, Sossalla, Samuel und Schach, Christian
(2025)
Right Ventricular Systolic Dysfunction Predicts Recovery of Left Ventricular Systolic Function and Reduced Quality of Life in Patients With Arrhythmia‐Induced Cardiomyopathy.
Clinical Cardiology 48 (2), e70070.
Veröffentlichungsdatum dieses Volltextes: 26 Feb 2025 06:39
Artikel
DOI zum Zitieren dieses Dokuments: 10.5283/epub.75067
Zusammenfassung
Introduction Arrhythmia-induced cardiomyopathy (AIC) is an underrecognized condition resulting in left ventricular systolic dysfunction (LVSD) that is primarily caused by atrial fibrillation (AFib). The relationship between AIC, right ventricular (RV) function, and quality of life (QoL) has not been well studied. Methods We performed a post-hoc analysis of our AIC trial in which we ...
Introduction
Arrhythmia-induced cardiomyopathy (AIC) is an underrecognized condition resulting in left ventricular systolic dysfunction (LVSD) that is primarily caused by atrial fibrillation (AFib). The relationship between AIC, right ventricular (RV) function, and quality of life (QoL) has not been well studied.
Methods
We performed a post-hoc analysis of our AIC trial in which we prospectively screened for patients with tachyarrhythmia and newly diagnosed, otherwise unexplained LVSD. Following rhythm restoration, patients were followed up at 2, 4, and 6 months. Only patients with persistent sinus rhythm were analyzed. RV function was assessed via echocardiography (tricuspid annular plane systolic excursion [TASPE] and fractional area change [FAC]) and QoL by the Minnesota Living with Heart Failure Questionnaire.
Results
Of a total of 50 patients recovering from LVSD, 41 were diagnosed with AIC and 9 with non-AIC. Initially, RV function was reduced in the AIC group and recovered after rhythm restoration, whereas no relevant changes were noted in the non-AIC group. QoL was reduced in both groups and also improved after rhythm restoration. Regression analysis identified low TAPSE as a predictive parameter for AIC diagnosis and worse QoL in AIC patients.
Conclusion
We demonstrated that RV function and QoL are impaired in patients with AIC. Six months after rhythm restoration, TAPSE may serve as an early indicator of AIC while also correlating with QoL. This underscores the importance of detailed echocardiographic evaluation with a focus on RV function in patients with concomitant tachyarrhythmia and LVSD.
Alternative Links zum Volltext
Beteiligte Einrichtungen
Details
| Dokumentenart | Artikel | ||||
| Titel eines Journals oder einer Zeitschrift | Clinical Cardiology | ||||
| Verlag: | Wiley | ||||
|---|---|---|---|---|---|
| Band: | 48 | ||||
| Nummer des Zeitschriftenheftes oder des Kapitels: | 2 | ||||
| Seitenbereich: | e70070 | ||||
| Datum | 22 Februar 2025 | ||||
| Institutionen | Medizin > Universitäres Herzzentrum Regensburg (UHR) | ||||
| Identifikationsnummer |
| ||||
| Stichwörter / Keywords | arrhythmia‐induced cardiomyopathy | atrial fibrillation | quality of life | right ventricular function | ||||
| Dewey-Dezimal-Klassifikation | 600 Technik, Medizin, angewandte Wissenschaften > 610 Medizin | ||||
| Status | Veröffentlicht | ||||
| Begutachtet | Ja, diese Version wurde begutachtet | ||||
| An der Universität Regensburg entstanden | Zum Teil | ||||
| URN der UB Regensburg | urn:nbn:de:bvb:355-epub-750670 | ||||
| Dokumenten-ID | 75067 |
Downloadstatistik
Downloadstatistik