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Pharmacological inhibitors of the cystic fibrosis transmembrane conductance regulator exert off-target effects on epithelial cation channels
Lin, JinHeng, Gettings, Sean M.
, Talbi, Khaoula, Schreiber, Rainer, Taggart, Michael J., Preller, Matthias , Kunzelmann, Karl, Althaus, Mike and Gray, Michael A.
(2023)
Pharmacological inhibitors of the cystic fibrosis transmembrane conductance regulator exert off-target effects on epithelial cation channels.
Pflügers Archiv - European Journal of Physiology 475 (2), pp. 167-179.
Date of publication of this fulltext: 18 Mar 2025 09:55
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| Item type | Article | ||||
| Journal or Publication Title | Pflügers Archiv - European Journal of Physiology | ||||
| Publisher: | SPRINGER HEIDELBERG | ||||
|---|---|---|---|---|---|
| Place of Publication: | HEIDELBERG | ||||
| Volume: | 475 | ||||
| Number of Issue or Book Chapter: | 2 | ||||
| Page Range: | pp. 167-179 | ||||
| Date | 2023 | ||||
| Institutions | Biology, Preclinical Medicine > Institut für Physiologie > Prof. Dr. Karl Kunzelmann | ||||
| Identification Number |
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| Keywords | CFTR INHIBITION; HCO3-SECRETION; ALPHA-SUBUNIT; CELL LINE; AMILORIDE; IDENTIFICATION; HOMEOSTASIS; CRACM1; CALU-3; CFTR inhibitors; Off-target effects; Store-operated calcium entry; Orai1; ENaC; In silico modelling | ||||
| Dewey Decimal Classification | 500 Science > 570 Life sciences | ||||
| Status | Published | ||||
| Refereed | Yes, this version has been refereed | ||||
| Created at the University of Regensburg | Yes | ||||
| Item ID | 75357 |
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