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A novel serum extracellular vesicle protein signature to monitor glioblastoma tumor progression

Tzaridis, Theophilos ; Weller, Johannes ; Bachurski, Daniel ; Shakeri, Farhad ; Schaub, Christina ; Hau, Peter ; Buness, Andreas ; Schlegel, Uwe ; Steinbach, Joachim‐Peter ; Seidel, Clemens ; Goldbrunner, Roland ; Schäfer, Niklas ; Wechsler‐Reya, Robert J. ; Hallek, Michael ; Scheffler, Björn ; Glas, Martin ; Haeberle, Lothar ; Herrlinger, Ulrich ; Coch, Christoph ; Reiners, Katrin S. ; Hartmann, Gunther



Abstract

Detection of tumor progression in patients with glioblastoma remains a major challenge. Extracellular vesicles (EVs) are potential biomarkers and can be detected in the blood of patients with glioblastoma. In our study, we evaluated the potential of serum-derived EVs from glioblastoma patients to serve as biomarker for tumor progression. EVs from serum of glioblastoma patients and healthy ...

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