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Fight INflammation to Improve outcome after aneurysmal Subarachnoid HEmorRhage (FINISHER) trial: Study protocol for a randomized controlled trial

Güresir, Erdem ; Lampmann, Tim ; Bele, Sylvia ; Czabanka, Marcus ; Czorlich, Patrick ; Gempt, Jens ; Goldbrunner, Roland ; Hurth, Helene ; Hermann, Elvis ; Jabbarli, Ramazan ; Krauthausen, Marius ; König, Ralph ; Lindner, Dirk ; Malinova, Vesna ; Meixensberger, Jürgen ; Mielke, Dorothee ; Németh, Robert ; Darkwah Oppong, Marvin ; Pala, Andrej ; Prinz, Vincent ; Rashidi, Ali ; Roder, Constantin ; Sandalcioglu, Ibrahim Erol ; Sauvigny, Thomas ; Schebesch, Karl-Michael ; Timmer, Marco ; Vajkoczy, Peter ; Wessels, Lars ; Wild, Florian ; Wilhelm, Christoph ; Wostrack, Maria ; Vatter, Hartmut ; Coch, Christoph



Abstract

Rationale: Aneurysmal subarachnoid hemorrhage (SAH) has high morbidity and mortality. While the primary injury results from the initial bleeding cannot currently be influenced, secondary injury through vasospasm and delayed cerebral ischemia worsens outcome and might be a target for interventions to improve outcome. To date, beside the aneurysm treatment to prevent re-bleeding and the ...

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