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High-fat diet impact on intestinal cholesterol conversion by the microbiota and serum cholesterol levels

Bubeck, Alena M. ; Urbain, Paul ; Horn, Cathrine ; Jung, Anna S. ; Ferrari, Lisa ; Ruple, Hannah K. ; Podlesny, Daniel ; Zorn, Stefanie ; Laupsa-Borge, Johnny ; Jensen, Caroline ; Lindseth, Inge ; Lied, Gülen Arslan ; Dierkes, Jutta ; Mellgren, Gunnar ; Bertz, Hartmut ; Matysik, Silke ; Krautbauer, Sabrina ; Liebisch, Gerhard ; Schoett, Hans-Frieder ; Dankel, Simon N. ; Fricke, W. Florian



Abstract

Cholesterol-to-coprostanol conversion by the intestinal microbiota has been suggested to reduce intestinal and serum cholesterol availability, but the relationship between intestinal cholesterol conversion and the gut microbiota, dietary habits, and serum lipids has not been characterized in detail. We measured conserved proportions of cholesterol high and low-converter types in individuals with ...

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