Effect of Arginine Vasopressin on Human Neutrophil Function Under Physiological and Sepsis-Associated Conditions

URN to cite this document:: urn:nbn:de:bvb:355-epub-764755
DOI to cite this document:: 10.5283/epub.76475

Haile, Sophie-Marie ; Gruber, Michael

; Bollwein, Gabriele ; Trabold, Benedikt

License: Creative Commons Attribution 4.0
PDF - Published Version
(1MB)

Date of publication of this fulltext: 27 Mar 2025 10:58

Alternative links to fulltext:DOI Publisher

Details

Preview

Export bibliographical data

Abstract

This study examines how different concentrations of arginine vasopressin (AVP) and its preservative chlorobutanol (ClB) impact the immune functions of human polymorphonuclear neutrophils (PMNs), which are crucial in the immune response, particularly in sepsis. Using a model to simulate the physiological, sepsis-related, and therapeutic AVP levels in plasma, we analysed how AVP and ClB affect PMN ...