Farkas, Stefan, Hornung, Matthias, Sattler, Christine, Edtinger, Karoline, Steinbauer, Markus, Anthuber, Matthias, Schlitt, Hans J., Herfarth, Hans and Geissler, Edward K. (2006) Blocking MAdCAM-1 in vivo reduces leukocyte extravasation and reverses chronic inflammation in experimental colitis. International journal of colorectal disease 21 (1), pp. 71-78.
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Other URL: http://dx.doi.org/10.1007/s00384-004-0709-y
Abstract
BACKGROUND: Leukocyte recruitment to sites of intestinal inflammation is a crucial multi-step process, leading ultimately to the accumulation of cells in the inflamed tissue. These interactions in the gut are critically dependent on the mucosal addressin cell adhesion molecule-1 (MAdCAM-1), which is expressed on endothelial cells within the mesenteric lymph nodes and the lamina propria of the ...
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| Item type: | Article | ||||||
|---|---|---|---|---|---|---|---|
| Date: | January 2006 | ||||||
| Institutions: | Medicine > Lehrstuhl für Innere Medizin I Medicine > Lehrstuhl für Chirurgie | ||||||
| Identification Number: |
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| Keywords: | MAdCAM-1; Experimental chronic colitis; In vivo microscopy | ||||||
| Dewey Decimal Classification: | 600 Technology > 610 Medical sciences Medicine | ||||||
| Status: | Published | ||||||
| Refereed: | Yes, this version has been refereed | ||||||
| Created at the University of Regensburg: | Yes | ||||||
| Item ID: | 770 |
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