Cold Atmospheric Plasma Improves the Therapeutic Success of Photodynamic Therapy on UV-B-Induced Squamous Cell Carcinoma in Hairless Mice

URN to cite this document:: urn:nbn:de:bvb:355-epub-770468
DOI to cite this document:: 10.5283/epub.77046

Arndt, Stephanie

; Unger, Petra ; Ivanova, Irina

; Bäumler, Wolfgang

; Drexler, Konstantin

; Berneburg, Mark

; Karrer, Sigrid

License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 03 Jul 2025 11:26

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Abstract

Background/Objectives: Actinic keratosis (AK) occurs on sun-damaged skin and is considered a precursor to squamous cell carcinoma (SCC). Photodynamic therapy (PDT), using 5-aminolevulinic acid (ALA) and red light, is a common treatment for AK. However, its clinical efficacy for invasive tumors such as SCC is limited by the poor penetration and distribution of the photosensitizer. Cold atmospheric ...