Cell-type specific effects of the long non-coding RNA HIF1A-AS3 on HIF1A expression in kidney cells

URN to cite this document:: urn:nbn:de:bvb:355-epub-774884
DOI to cite this document:: 10.5283/epub.77488

Reichelt-Wurm, Simone

; Knauss, Lena ; Strasser, Bettina ; Scharf, Mona ; Holler, Kathrin ; Eggenhofer, Elke ; Kretz, Markus ; Banas, Bernhard ; Banas, Miriam C.

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Date of publication of this fulltext: 04 Aug 2025 09:30

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Abstract

The hypoxia-inducible factor 1α (Hif1α) represents the master transcription factor coordinating cellular responses to oxygen depletion. With hundreds of target genes it plays a key role in numerous bio-medical conditions as well as neoplastic and non-cancerous diseases, which in turn requires a strict regulation. Long non-coding RNAs have the potential to virtually control every step of gene ...