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Expanding the Repertoire of Photoswitchable Unnatural Amino Acids for Enzyme Engineering

URN to cite this document:
urn:nbn:de:bvb:355-epub-775028
DOI to cite this document:
10.5283/epub.77502
Hiefinger, Caroline ; Marcon, Michela ; Pape, Verena ; Casadevall, Guillem ; Lahmy, Ranit ; Haag, Christoph ; Nazet, Julian ; Bartl, Michael ; Bruckmann, Astrid ; Osuna, Sílvia ; König, Burkhard ; Hupfeld, Andrea
Date of publication of this fulltext: 06 Aug 2025 08:35

This publication is part of the DEAL contract with Wiley.


Abstract

Photoswitchable unnatural amino acids (psUAAs) play a crucial role in the engineering of light-sensitivity in enzymes, which holds significant promise for diverse applications such as biotherapy and biocatalysis. Besides near-quantitative photoconversion, the success and expediency of a psUAA for a certain application is defined by its interaction potential with the enzyme, its thermal stability ...

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