This article advocates for interdisciplinary perspectives in the study of remote borderland areas. Highlighting the strong overlaps between International Relations Theory (IRT) and border studies, it argues that transnational dynamics are evident in border regions that are characterized by multiple forms of remoteness. More specifically, it shows that borders are a critical object of transnationalism. Viewing transnationalism as a liberal strand within IRT, it is contended that transnationalists and post-modern border scholars can find common ground to sharpen their understanding of cross-border dynamics in remote locations. Focusing on the border between Tajikistan and Afghanistan as a case study, the article offers insights into how interdisciplinarity can inform transnational relations. This approach can serve as a foundation for further research aimed at stressing interdisciplinary dialogue in international studies.