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Influence of mode of delivery on neonatal QTc
Article
Eder, Christina, Gerling, Stephan
, Brandstetter, Susanne
, Dechant, Markus-Johann, Köninger, Angela, Schnabel, Annegret, Apfelbacher, Christian J.
, Wellmann, Sven
, Kabesch, Michael
, Ambrosch, Andreas, Arndt, Petra A., Baessler, Andrea, Berneburg, Mark
, Brunner, Romuald
, Malfertheiner, Sara Fill
, Franke, André, Häsler, Robert, Heid, Iris M., Heinze, Stefanie, Högler, Wolfgang, Kerzel, Sebastian
, Koller, Michael
, Leitzmann, Michael
, Lennon, Áine M.
, Rothfuß, David, Promm, Martin, Schaub, Bianca, Weidinger, Stephan and Michel, Holger
(2026)
Influence of mode of delivery on neonatal QTc.
Journal of Perinatology.
DOI to cite this document: 10.5283/epub.78987
Abstract
Objective: To evaluate the influence of mode of delivery on repolarisation and QT interval in the neonatal electrocardiogram (ECG). Study design: KUNO-Kids is a prospective, population-based birth cohort study. Neonates received an ECG within the first week of life; subgroups were divided according to mode of delivery. Effects on neonatal QT interval were tested by linear and logistic ...
Objective:
To evaluate the influence of mode of delivery on repolarisation and QT interval in the neonatal electrocardiogram (ECG).
Study design:
KUNO-Kids is a prospective, population-based birth cohort study. Neonates received an ECG within the first week of life; subgroups were divided according to mode of delivery. Effects on neonatal QT interval were tested by linear and logistic regression analyses, adjusting for age at ECG recording.
Results:
In total, 712 neonates were included. The primary caesarean section group showed a significant higher mean QTc (regression coefficient 6.03, p = 0.033) and a significantly increased rate of prolonged QTc >450 ms (odds ratio 2.4, p = 0.042), compared to the spontaneous delivery group.
Conclusion:
The mode of delivery has a significant effect on neonatal QTc. Clinicians should consider this influence when deciding on postnatal and follow-up examinations, regarding additional risk factors for acquired long QT interval.
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Details
| Item type | Article | ||||
| Journal or Publication Title | Journal of Perinatology | ||||
| Publisher | Springer | ||||
| Open Access Type | DEAL (Springer) | ||||
| Date | 16 March 2026 | ||||
| Date of publication | 19 Mar 2026 11:36 | ||||
| Institutions | Medicine > Lehrstuhl für Kinder- und Jugendmedizin | ||||
| Projects |
Verbundprojekt SysINFLAME: mono- und oligogenetische Eigenschaften als Zugang zur Systemmedizin, CP1
Funded by:
Bundesministerium für Bildung und Forschung (BMBF)
(01ZX1306E)
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| Identification Number |
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| Keywords | Medical research; Risk factors | ||||
| Dewey Decimal Classification | 600 Technology > 610 Medical sciences Medicine | ||||
| Status | Published | ||||
| Refereed | Yes, this version has been refereed | ||||
| Created at the University of Regensburg | Partially | ||||
| URN of the UB Regensburg | urn:nbn:de:bvb:355-epub-789876 | ||||
| Item ID | 78987 |
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